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. 2019 May 13;18(1):792–803. doi: 10.3892/ol.2019.10348

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Copyright: © He et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Immunohistochemical assessment of ERβ1 expression in lung adenocarcinoma tissue specimens. (A) The Allred scoring system of ERβ1 expression in tissue specimens. Cytoplasmic score of 8 + nuclear score of 8=total score of 16 (tissue specimen from a patient with EGFR Del19 mutation). (B) The cytoplasmic score of 3 + nuclear score of 7=total score of 10 (tissue specimen from a patient with EGFR exon 21 L858R mutation). (C) The cytoplasmic score 0 + nuclear score 0=total score 0 (tissue specimen from a patient without any EGFR mutation). Scale bar, 100 µm. ERβ1, estrogen receptor β1; EGFR, epidermal growth factor.