Table 1.
C-attribution in the spectrogram of Impurity X.
| Location | 13C-NMR | DEPT | HSQC (Contain 1H-NMR) | HMBC |
|---|---|---|---|---|
| 1 | 139.35 | quaternary carbon | - | - |
| 2 | 116.25 | quaternary carbon | - | - |
| 3 | 113.84 | quaternary carbon | - | - |
| 4 | 140.26 | quaternary carbon | - | - |
| 5 | 138.78 | quaternary carbon | - | - |
| 6 | 135.19 | quaternary carbon | - | - |
| 7 | 119.72 | CH | 6.46, 6.49 (1H, J = 7.5 Hz) | 139.35, 116.25, 113.84 |
| 8 | 128.85 | CH | 5.56, 5.58 (1H, J = 7.5 Hz) | 116.25, 40.87,25.58 |
| 10 | 40.87 | CH2 | 1.97 | 134.85, 124.15, 26.84 |
| 11 | 22.89 | CH2 | 2.15 (2H) | 39.83, 26.84 |
| 12 | 124.15 | CH | 5.08 (9H) | 39.83, 26.84,16.15 |
| 13 | 134.85 | quaternary carbon | - | - |
| 14 | 39.83 | CH2 | 1.97, 1.98, 1.99 (mutiple H) | 134.85, 124.15, 26.84, 16.15 |
| 15 | 26.84 | CH2 | 2.06, 2.07, 2.09 (mutiple H) | 134.85, 124.15, 123.95, 39.83 |
| 16 | 123.95 | CH | 5.10 (1H) | 39.83, 26.84, 16.15 |
| 17 | 131.06 | quaternary carbon | - | - |
| 18 | 17.82 | CH3 | 1.58 (3H) | 131.06, 124.15 |
| 19 | 25.80 | CH3 | 1.67 (3H) | 131.06, 123.95, 17.82 |
| 20 | 10.49 | CH3 | 2.15 (3H) | 140.26, 116.25, 113.84 |
| 21 | 25.58 | CH3 | 1.38 (3H) | 128.85, 40.87, 16.15 |
| 22 | 16.15 | CH3 | 1.59 (mutiple H) | 134.85, 124.15, 39.83, 26.84 |
| -OCH3 | 61.39 | CH3 | 3.93 | 140.26 |
| -OCH3 | 61.01 | CH3 | 3.87 | 139.95 |