AT/RT |
Atypical Teratoid Rhabdoid Tumor |
AURK |
Aurora Kinase |
AURKA |
Aurora Kinase A |
AURKB |
Aurora Kinase B |
AURKC |
Aurora Kinase C |
B3LYP |
Becke-3-Lee Yang Parr |
BBB |
Blood Brain Barrier |
CNS MPO |
Central Nervous System Multi-Parameter Optimization |
CYP450 |
Cytochrome P450 |
DFT |
Density Functional Theory |
EBT |
Embryonal Brain Tumor |
G3-MB |
Group 3 MB |
G4-MB |
Group 4 MB |
GBM |
Glioblastoma multiforme |
hERG |
Human Ether-a-go-go-related gene |
IC50
|
Half Maximal Inhibitory Concentration |
LogP |
Lipophilicity |
MB |
Medulloblastoma |
MRT |
Malignant Rhabdoid Tumor |
MW |
Molecular Weight |
PB |
Polo-box |
PBD |
Protein Data Bank |
PI |
Propidium Iodide |
PK |
Protein Kinase |
PKI |
Protein Kinase Inhibitor |
PLK |
Polo-like Kinase |
PLK4 |
Polo-like kinase 4 |
PLK4i |
Polo-like kinase 4 inhibitor |
PSA |
Polar Surface Area |
RT |
Rhabdoid Tumor |
SAR |
Structure-Activity Relationship |
SHH |
Sonic hedgehog |
STM |
Signal Transduction Modifiers |
TPSA |
Total Polar Surface Area |
TRK |
Tropomyosin Receptor Kinase |