Glycidamide (GA) promotes cell growth and migration and contributes to malignant phenotypes of prostate cancer cells. (A) Chemical structure of glycidamide (GA). (B) The effects of GA on cell viability were determined in a panel of prostate cancer cell lines. Cells were treated with GA at the indicated concentrations in a10% fetal bovine serum (FBS)-supplemented medium for 24, 48, and 72 h, and cell viability was assessed using a crystal violet staining method. Bars, SD (n = 6). (C,D) The effects of GA on the migratory activity of a panel of prostate cancer cell lines after 24 h of treatment. * p < 0.05, ** p < 0.01, *** p < 0.001. Values are presented as the mean ± SD of three independent experiments. SD: standard deviation.