Table V.
Correlation between a particular population of inflammatory infiltrates located in the center of the tumor and disease progression parameters in patients with colorectal cancer.
| Variables | N | Neutrophils | Macrophages | Eosinophils |
|---|---|---|---|---|
| Venous invasion | ||||
| Absent | 123 | −0.432 | ||
| Present | 21 | NS | <0.010 | NS |
| Lymphatic invasion | ||||
| Absent | 118 | NS | NS | NS |
| Present | 26 | |||
| Perineural invasion | ||||
| Absent | 134 | NS | NS | NS |
| Present | 10 | |||
| Lymph node metastasis | ||||
| Absent | 71 | NS | NS | NS |
| Present | 73 | |||
| Distant metastasis | ||||
| Absent | 129 | NS | NS | NS |
| Present | 15 | |||
| Tumor deposits | ||||
| Absent | 122 | 0.354 | −0.220 | −0.158 |
| Present | 22 | 0.000 | 0.008 | 0.000 |
| Size of tumor deposits (mm) | ||||
| <2.5 | 12 | 0.170 | −0.203 | NS |
| ≥2.5 | 10 | 0.041 | 0.015 | |
| K-M grade | ||||
| Low | 76 | NS | NS | NS |
| High | 68 | |||
| Tumor budding | ||||
| Absence | 86 | NS | NS | NS |
| Presence | 58 | |||
| Crohn's-like aggregates of lymphocyte | ||||
| Absence | 112 | NS | NS | 0.236 |
| Presence | 32 | <0.010 | ||
| Necrosis | ||||
| Absent | 42 | NS | NS | NS |
| Focal | 51 | |||
| Moderate | 34 | |||
| Extensive | 17 | |||
| Fibrosis | ||||
| Absent | 9 | NS | NS | NS |
| Focal | 67 | |||
| Moderate | 38 | |||
| Extensive | 30 | |||
| Maturation of fibrotic stroma | ||||
| Immature | 10 | NS | NS | NS |
| Intermediate | 84 | |||
| Mature | 50 |
NS, not significant.