. 2019 May 6;18(1):465–471. doi: 10.3892/ol.2019.10318

Table III.

Univariate and multivariate Cox regression analysis of overall survival time in 90 patients with gastric cancer.

	Univariate analysis			Multivariate analysis

Variable	HR	95% CI	P-value	HR	95% CI	P-value
Age: <65 vs. ≥65 years	1.518	0.906–2.544	0.113
Sex: Female vs. male	0.936	0.516–1.698	0.827
Maximum tumor diameter: <5 vs. ≥5 cm	2.559	1.401–4.677	0.002^a	1.818	0.986–3.351	0.056
Histological differentiation: Moderate-high vs. poor	1.480	0.815–2.687	0.198
Depth of invasion: T1-2 vs. T3-4	6.817	1.661–27.980	0.008^a	10.038	1.329–75.839	0.025a
Lymph node metastasis: N0 vs. N+	2.595	1.314–5.122	0.006^a	2.167	0.793–5.922	0.132
Distant metastasis: M0 vs. M1	2.251	0.809–6.261	0.120
TNM stage: I/II vs. III/IV	2.586	1.488–4.495	0.001^a	1.138	0.505–2.564	0.756
MSRB3 expression: Low vs. high	1.817	1.013–3.257	0.045^a	1.813	1.001–3.281	0.049^a

P<0.05. CI, confidence interval; GC, gastric cancer; HR, hazard ratio; MSRB3, methionine sulfoxide reductases B3; TNM, Tumor-Node-Metastasis.