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. 2019 May 28;21:130. doi: 10.1186/s13075-019-1907-x

Fig. 2.

Fig. 2

DAS28-CRP change from baseline up to week 48 (TP2 per-protocol set). Analyzed using a repeated measures analysis of (co)variance with treatment and time as factors up to week 48. TP2 PPS comprised all patients completing the study until week 48 without major protocol deviations. CRP, C-reactive protein; DAS28, disease activity score including 28 joint count; PPS, per-protocol set; SE, standard error; TP, treatment period