Study	Reason for exclusion
Adis 2006	Not RCT ‐ general review of naproxen sodium/metoclopramide formulation from Pozen Inc. Data from the Pozen studies are included in Appendix 8
Andersson 1989	Did not use IHS diagnostic criteria (or equivalent) for migraine ‐ diagnostic criteria judged not equivalent to IHS criteria
Johnson 1985	Did not use IHS diagnostic criteria (or equivalent) for migraine ‐ no diagnostic criteria reported
Krymchantowski 2005	Not randomised. Quasi‐randomised only
Misra 2010	Fewer than 10 participants/treatment arm
NCT01726920	Not double blind
Nestvold 1985	Did not use IHS diagnostic criteria (or equivalent) for migraine ‐ diagnostic criteria judged not equivalent to IHS criteria
Nestvold 1986	Supplement article, not original study report (same study as Nestvold 1985), no additional data
Pradalier 1985	Did not use IHS diagnostic criteria (or equivalent) for migraine ‐ diagnostic criteria judged not equivalent to IHS criteria
Sargent 1988	Did not use IHS diagnostic criteria (or equivalent) for migraine ‐ diagnostic criteria judged not equivalent to IHS criteria
Smith 2007	Same study as Smith 2005, but reporting only quality‐of‐life and satisfaction outcomes
Stronks 2003	Low patient numbers (12 only). No data on individual attacks. A comparative study versus naratriptan without placebo
Treves 1992	Did not use IHS diagnostic criteria (or equivalent) for migraine ‐ diagnostic criteria judged not equivalent to IHS criteria
Welch 1986	Supplement article, not original study report

IHS: International Headache Society; RCT: randomised controlled trial.