| Summary of results: relief of headache‐associated symptoms at two hours | ||||||
| Intervention | Studies | Attacks with symptom present | Treatment (%) | Placebo (%) | Relative benefit (95% CI) | NNT (95% CI) |
| Nausea | ||||||
| Naproxen 500/825 mg vs placebo | 3 | 782 | 39 | 23 | 1.7 (1.4 to 2.1) | 6.1 (4.4 to 11) |
| Naproxen 500 mg vs placebo | 2 | 686 | 36 | 21 | 1.7 (1.3 to 2.2) | 6.8 (4.7 to 12) |
| Photophobia | ||||||
| Naproxen 500/825 mg vs placebo | 3 | 1342 | 32 | 19 | 1.7 (1.4 to 2.1) | 7.3 (5.5 to 11) |
| Naproxen 500 mg vs placebo | 2 | 1185 | 31 | 18 | 1.7 (1.4 to 2.1) | 7.7 (5.6 to 12) |
| Phonophobia | ||||||
| Naproxen 500/825 mg vs placebo | 3 | 1303 | 35 | 23 | 1.7 (1.4 to 2.0) | 7.2 (5.3 to 11) |
| Naproxen 500 mg vs placebo | 2 | 1146 | 32 | 20 | 1.6 (1.3 to 2.0) | 8.1 (5.7 to 14) |
| CI: confidence interval; NNT: number needed to treat. | ||||||
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