Table 4.
Percentage of variation (Δ) of echocardiographic parameters between twelve and two weeks post-infarction
| AL (n = 26) | AL/IF (n = 28) | IF (n = 20) | |
|---|---|---|---|
| BW | 7.86 (4.17–11.6) | 4.35 (−2.61–6.90) | 11.0 (9.57–13.0)# |
| HR | 4.73 ± 15.4 | 4.25 ± 17.0 | −7.91 ± 8.00*# |
| LVDD | 7.61 ± 5.14 | 2.33 ± 8.45 | 2.85 ± 6.47 |
| LVSD | 6.02 ± 12.1 | 3.07 ± 13.2 | 6.75 ± 10.7 |
| LA | 8.40 ± 17.1 | 4.74 ± 9.87 | −1.43 ± 15.0 |
| E-wave | 7.65 ± 33.9 | −5.71 ± 17.2 | − 14.4 ± 14.5* |
| A-wave | 18.6 (−11.1–86.7) | −6.97 (−23.0–12.7) | −1.02 (−34.8–31.2) |
| E/A | 0.23 (−47.5–15.1) | −8.14 (− 25.6–37.7) | −4.78 (− 34.2–29.2) |
| IVRT | 14.6 ± 21.0 | 3.90 ± 22.9 | − 2.96 ± 21.9 |
| IVRTn | 16.7 ± 21.1 | 5.21 ± 22.3 | − 7.08 ± 20.7* |
| EDT | - 6.13 ± 20.7 | − 11.1 ± 20.7 | 12.2 ± 30.6# |
| LV diastolic area | 10.6 ± 12.0 | 8.89 ± 14.7 | 5.27 ± 18.5 |
| LV systolic area | 8.37 ± 22.9 | 12.1 ± 19.9 | 3.17 ± 19.0 |
| Δ Area | 9.13 ± 30.0 | −3.06 ± 29.9 | 9.06 ± 35.0 |
| MI size | −9.76 (−14.9- -2.49) | −4.13 (− 12.9–9.51) | − 13.2 (−23.7- -6.52)# |
Data as mean ± standard deviation or median and 25th and 75th percentiles. AL: ad libitum fed; AL/IF: ad libitum before myocardial infarction (MI) and intermittently fasted after MI; IF: intermittently fasted before and after MI. Δ was calculated as [(final value minus initial value)/initial value] X 100. BW: body weight; HR: heart rate; LVDD and LVSD: left ventricular (LV) diastolic and systolic diameters, respectively; LA: left atrial diameter; E-wave and A-wave: early and late diastolic mitral inflow, respectively; IVRT: isovolumic relaxation time; IVRTn: IVRT normalized to heart rate; EDT: E-wave deceleration time; Δ Area: fractional area change. ANOVA and Tukey or Kruskal-Wallis and Dunn; * p < 0.05 vs AL; # p < 0.05 vs AL/IF