Figure 3.
Effect of histone deacetylase inhibitors on ABCC1, ABCC2, ABCC3, ABCC4 and ABCG2 expression levels. A549 and HCT116 cells were treated with DMSO, SAHA (0.5 µM) or TSA (100 nM) for 24 h. (A) mRNA and (B) protein expression levels of ABCC1, ABCC2, ABCC3, ABCC4 and ABCG2 were measured using reverse transcription-quantitative polymerase chain reaction and western blotting, respectively. *P<0.05 and **P<0.01, vs. DMSO group. ABC, ATP-binding cassette; SAHA, suberoylanilide hydroxamic acid; TSA, trichostatin A.
