Table 3.
Statistically significant GO cellular components (CC) derived from ubiquitinated proteins in human pituitary adenomas.
| ID | Cellular components | GeneRatio | BgRatio | P-value | P.adjust | Q-value | GeneID | Count |
|---|---|---|---|---|---|---|---|---|
| GO:0022627 | Cytosolic small ribosomal subunit | 4/33 | 45/19659 | 9.34E-07 | 1.33E-04 | 8.26E-05 | RPS3/RPS20/HBA1/HBA2 | 4 |
| GO:0015935 | Small ribosomal subunit | 4/33 | 73/19659 | 6.60E-06 | 4.68E-04 | 2.92E-04 | RPS3/RPS20/HBA1/HBA2 | 4 |
| GO:0022626 | Cytosolic ribosome | 4/33 | 115/19659 | 3.99E-05 | 1.89E-03 | 1.18E-03 | RPS3/RPS20/HBA1/HBA2 | 4 |
| GO:0044445 | Cytosolic part | 5/33 | 250/19659 | 5.67E-05 | 2.01E-03 | 1.25E-03 | IDE/RPS3/RPS20/HBA1/HBA2 | 5 |
| GO:0072562 | Blood microparticle | 4/33 | 147/19659 | 1.04E-04 | 2.95E-03 | 1.83E-03 | FGA/ALB/HBA1/HBA2 | 4 |
| GO:0031838 | Haptoglobin-hemoglobin complex | 2/33 | 11/19659 | 1.49E-04 | 3.17E-03 | 1.97E-03 | HBA1/HBA2 | 2 |
| GO:0005833 | Hemoglobin complex | 2/33 | 12/19659 | 1.78E-04 | 3.17E-03 | 1.97E-03 | HBA1/HBA2 | 2 |
| GO:0060198 | Clathrin-sculpted vesicle | 2/33 | 12/19659 | 1.78E-04 | 3.17E-03 | 1.97E-03 | DNAJC5/SLC32A1 | 2 |
| GO:0044391 | Ribosomal subunit | 4/33 | 191/19659 | 2.83E-04 | 4.47E-03 | 2.78E-03 | RPS3/RPS20/HBA1/HBA2 | 4 |
| GO:0071682 | Endocytic vesicle lumen | 2/33 | 19/19659 | 4.59E-04 | 6.52E-03 | 4.06E-03 | HBA1/HBA2 | 2 |
| GO:0005840 | Ribosome | 4/33 | 276/19659 | 1.13E-03 | 1.46E-02 | 9.07E-03 | RPS3/RPS20/HBA1/HBA2 | 4 |
| GO:0060205 | Cytoplasmic vesicle lumen | 4/33 | 338/19659 | 2.37E-03 | 2.62E-02 | 1.63E-02 | FGA/ALB/HBA1/HBA2 | 4 |
| GO:0031983 | Vesicle lumen | 4/33 | 339/19659 | 2.40E-03 | 2.62E-02 | 1.63E-02 | FGA/ALB/HBA1/HBA2 | 4 |
| GO:0098563 | Intrinsic component of synaptic vesicle membrane | 2/33 | 46/19659 | 2.70E-03 | 2.74E-02 | 1.71E-02 | DNAJC5/SLC32A1 | 2 |
| GO:0035577 | Azurophil granule membrane | 2/33 | 58/19659 | 4.26E-03 | 4.03E-02 | 2.51E-02 | DNAJC5/TMEM30A | 2 |
| GO:0030658 | Transport vesicle membrane | 3/33 | 204/19659 | 4.78E-03 | 4.24E-02 | 2.64E-02 | DNAJC5/SLC32A1/TMEM30A | 3 |
| GO:0031093 | Platelet alpha granule lumen | 2/33 | 67/19659 | 5.64E-03 | 4.71E-02 | 2.94E-02 | FGA/ALB | 2 |
| GO:0031300 | Intrinsic component of organelle membrane | 3/33 | 226/19659 | 6.34E-03 | 4.98E-02 | 3.10E-02 | DNAJC5/SLC32A1/ITM2B | 3 |
| GO:0005844 | Polysome | 2/33 | 73/19659 | 6.67E-03 | 4.98E-02 | 3.10E-02 | VIM/RPS3 | 2 |
GeneRatio = The ratio of the number of genes enriched by the CC to the total number of genes enriched. BgRatio = The ratio of the number of genes contained in the CC to the number of genes in the BP database.