Table 5.
Statistically significant GO molecular functions (MF) derived from ubiquitinated proteins in human pituitary adenomas.
| ID | Molecular functions | GeneRatio | BgRatio | P-value | P.adjust | Q-value | GeneID | Count |
|---|---|---|---|---|---|---|---|---|
| GO:0019825 | Oxygen binding | 3/31 | 36/17632 | 3.38E-05 | 4.97E-03 | 3.48E-03 | ALB/HBA1/HBA2 | 3 |
| GO:0031720 | Haptoglobin binding | 2/31 | 10/17632 | 1.33E-04 | 8.10E-03 | 5.68E-03 | HBA1/HBA2 | 2 |
| GO:0001540 | Amyloid-beta binding | 3/31 | 61/17632 | 1.65E-04 | 8.10E-03 | 5.68E-03 | IDE/ITM2C/ITM2B | 3 |
| GO:0005344 | Oxygen carrier activity | 2/31 | 14/17632 | 2.69E-04 | 9.87E-03 | 6.93E-03 | HBA1/HBA2 | 2 |
| GO:0043177 | Organic acid binding | 4/31 | 204/17632 | 4.29E-04 | 1.12E-02 | 7.84E-03 | ALB/PAM/HBA1/HBA2 | 4 |
| GO:0016209 | Antioxidant activity | 3/31 | 86/17632 | 4.56E-04 | 1.12E-02 | 7.84E-03 | ALB/HBA1/HBA2 | 3 |
| GO:0050699 | WW domain binding | 2/31 | 31/17632 | 1.35E-03 | 2.83E-02 | 1.99E-02 | NDFIP1/TCEAL2 | 2 |
| GO:0048037 | Cofactor binding | 5/31 | 495/17632 | 1.59E-03 | 2.92E-02 | 2.05E-02 | ALB/PAM/RPS3/HBA1/HBA2 | 5 |
| GO:0140104 | Molecular carrier activity | 2/31 | 43/17632 | 2.58E-03 | 4.22E-02 | 2.96E-02 | HBA1/HBA2 | 2 |
GeneRatio = The ratio of the number of genes enriched by the MF to the total number of genes enriched. BgRatio = The ratio of the number of genes contained in the MF to the number of genes in the BP database.