Table 2.
Effect of emodin on liver function tests.
| Group | ALT (U/L) | AST (U/L) | DBIL (μmol/L) | TBIL (μmol/L) | GTT (U/L) | ALP (King unit/100 ml) | TBA (μmol/L) |
|---|---|---|---|---|---|---|---|
| Emodin (20 mg/kg) | 55.4 2.7*@% | 67.6 3.4*@% | 41.9 2.7*# | 73.1 4.6*@% | 47.3 2.3*@& | 46.3 2.3*@% | 142.9 7.1*@% |
| Emodin (40 mg/kg) | 48.6 3.2*@%
|
62.0 3.5*@%
|
39.4 3.1*# | 59.1 4.6*@% | 42.4 3.0*@% | 42.9 2.4*@% | 99.5 3.5*@%
|
| Emodin (80 mg/kg) | 60.0 3.8*@& | 74.4 3.0*@& | 44.3 2.4* | 78.0 4.4*@& | 51.7 3.1*@ | 50.1 2.0*@& | 120.4 4.2*@%
|
| UDCA | 69.1 3.3*@ | 82.8 3.7*# | 45.3 3.5* | 85.7 4.3*@ | 54.7 3.0*# | 54.5 3.3*# | 157.1 5.0*@% |
| DXM | 72.1 3.1*@ | 86.3 3.5* | 48.5 3.1* | 95.3 5.0*# | 58.1 2.6* | 58.9 1.9*# | 186.6 5.9*@ |
| Model | 85.1 1.8* | 95.8 3.7* | 52.3 3.1* | 114.6 5.6* | 66.2 2.8* | 66.9 2.6* | 221.3 8.7* |
| Control | 24.8 3.3 | 27.5 2.4 | 19.8 1.9 | 44.1 3.4 | 15.7 1.4 | 30.2 1.1 | 47.4 2.2 |
Data were shown as mean ± SD. n = 6. (∗P < 0.01 vs. control group; #P < 0.05, @P < 0.01 vs. model group; &P < 0.05, %P < 0.01 vs. DXM group; P < 0.01 vs. UDCA group.)