Table 1.
The pupil light reflex (PLR) metrics (mean ± SEM) with 5,000 ms pulses and 1,000 ms pulses for different photoreceptor isolating conditions.
| Photoreceptor directed stimulation | |||||||
|---|---|---|---|---|---|---|---|
|
Pupil metrics 5,000 ms pulse |
Mel (17%)* |
L+M (10%) |
S (10%) |
L–M (6%) |
L+M + Mel |
S + Mel |
L–M + Mel |
| PLR Latency (ms) | 633.3 ± 43.3 | 341.7 ± 49.3 | 491.7 ± 64.4 | 325.0 ± 4.8 | 412.5 ± 45.8 | 579.2 ± 81.5 | 354.2 ± 12.5 |
| Peak Constriction Amplitude (%) | 3.2 ± 0.2 | 4.5 ± 0.6 | 3.1 ± 0.2 | 8.9 ± 0.4 | 4.8 ± 0.3 | 3.8 ± 0.4 | 8.5 ± 0.7 |
| Time to Peak (s) | 4.0 ± 0.3 | 0.9 ± 0.1 | 1.2 ± 0.2 | 0.8 ± 0.04 | 1.7 ± 0.6 | 2.8 ± 0.8 | 0.9 ± 0.1 |
| Constriction Velocity (%.s−1) | 0.8 ± 0.02 | 5.0 ± 1.0 | 2.6 ± 0.3 | 11.1 ± 1.0 | 3.6 ± 0.8 | 1.7 ± 0.4 | 9.8 ± 1.2 |
| 1.8 s PIPR (%) | 3.9 ± 0.7 | 0.1 ± 0.1 | 2.1 ± 0.5 | 2.1 ± 1.0 | 3.9 ± 0.7 | 4.1 ± 0.6 | 5.4 ± 0.6 |
|
Pupil metrics 5,000 ms pulse |
Mel (17%)* |
L+M (10%) |
S (10%) |
L–M (6%) |
L+M + Mel |
S + Mel |
L–M + Mel |
| PLR Latency (ms) | 612.5 ± 42.7 | 395.8 ± 46.3 | 445.8 ± 114.3 | 366.7 ± 9.6 | 379.2 ± 48.8 | 425.0 ± 62.9 | 341.7 ± 22.1 |
| Peak Constriction Amplitude (%) | 2.1 ± 0.2 | 3.1 ± 0.2 | 2.1 ± 0.3 | 7.0 ± 1.0 | 3.4 ± 0.2 | 2.5 ± 0.4 | 7.6 ± 0.7 |
| Time to Peak (s) | 0.9 ± 0.1 | 0.8 ± 0.03 | 0.9 ± 0.1 | 0.7 ± 0.01 | 0.9 ± 0.1 | 0.8 ± 0.1 | 0.8 ± 0.03 |
| Constriction Velocity (%.s−1) | 2.3 ± 0.4 | 4.1 ± 0.3 | 2.6 ± 0.6 | 9.9 ± 1.6 | 4.1 ± 0.5 | 3.0 ± 0.3 | 10.0 ± 1.3 |
| 1.8 s PIPR (%) | 1.9 ± 0.1 | 0.3 ± 0.2 | 1.1 ± 0.3 | 0.6 ± 0.1 | 2.1 ± 0.1 | 2.4 ± 0.4 | 3.0 ± 0.3 |
The units for the metrics and Weber contrasts of the photoreceptor isolating conditions are given in the parentheses. Mel, melanopsin; PIPR, post-illumination pupil response.
*
Measured with temporal white noise (without penumbral cones).