| Methods |
RCT, Double blind, single oral dose, parallel groups, local anaesthetic. Assessed by observer at 0, 1/2, 1 hr then hourly for 5 hours. Medication taken when pain of moderate to severe intensity. |
| Participants |
Urogenital surgery
n = 90 (30 relevant patients)
Age: adult |
| Interventions |
Dextropropoxyphene HCl 65 mg, n = 15
Placebo, n = 15 |
| Outcomes |
PI (4 point scale) standard
PR (5 point scale) nonstandard
Dextropropoxyphene was not significantly better than placebo (P not given)
Mean SPID @ 5 hrs: Dextropropoxyphene :4.5 Placebo: 3.3 |
| Notes |
Remedication allowed at 4 hours if no pain relief. If remedicated before 4 hours patients were withdrawn from the study.
There were no exclusions or withdrawals.
No serious adverse effects were reported & no patients withdrew as a result.
Dextropropoxyphene: 1/15 patients reported 1 adverse event
Placebo: 0/15
QS = 4 |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment? |
Low risk |
A ‐ Adequate |
