Table 6.
Oral |
Inhalation |
|||||
---|---|---|---|---|---|---|
Toxin | LD50
(μg kg −1) |
Relevant clinical detection levela (ng mL−1) |
Relevant detection level in 100 mL food (μg kg −1) |
LD50
(μg kg−1) |
Relevant clinical detection levela (pg mL−1) |
Reference |
BoNT | 1 | 14 | 0.7 | 0.003 | 42 | 1 |
Ricin | 10 000 | 140 000 | 7000 | 3 | 42 000 | 73 and 74 |
SEBb | — | — | — | 0.02 | 280 | 32 |
Stx-1c | 8 | 112 | 5.6 | 8 | 112 000 | 75 |
Stx-2c | 0.29 | 4 | 0.2 | 0.29 | 4000 | 76 |
Relevant clinical detection level calculated as the minimal concentration of toxin to detect an exposure equivalent to the LOD assuming an average weight person (70 kg) with 5 L of blood in circulation.
For SEB, the oral LD50 value has not been reported.
For Stx-1 and Stx-2, the oral and inhalational LD50 values are based upon the intraperitoneal LD50.