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. Author manuscript; available in PMC: 2019 May 29.
Published in final edited form as: Analyst. 2014 Aug 12;139(20):5093–5102. doi: 10.1039/c4an01270d

Table 6.

Established oral and inhalational LD50 values


Oral
Inhalation
Toxin LD50
(μg kg −1)
Relevant clinical
detection levela (ng mL−1)
Relevant detection
level in 100 mL food (μg kg −1)
LD50
(μg kg−1)
Relevant clinical detection
levela (pg mL−1)
Reference

BoNT 1 14 0.7 0.003 42 1
Ricin 10 000 140 000 7000 3 42 000 73 and 74
SEBb 0.02 280 32
Stx-1c 8 112 5.6 8 112 000 75
Stx-2c 0.29 4 0.2 0.29 4000 76
a

Relevant clinical detection level calculated as the minimal concentration of toxin to detect an exposure equivalent to the LOD assuming an average weight person (70 kg) with 5 L of blood in circulation.

b

For SEB, the oral LD50 value has not been reported.

c

For Stx-1 and Stx-2, the oral and inhalational LD50 values are based upon the intraperitoneal LD50.