Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The general architecture of a chimeric antigen receptor consists of a single-chain variable fragment derived against a predetermined tumor-associated antigen followed by a CD3ζ domain required for provision of signal 1 and T-cell activation upon antigen recognitionBayraktar
