Table 1.
Patient Characteristics by Reconstruction Laterality and Procedure Type
| Variable | Unilateral |
Bilateral |
||||
|---|---|---|---|---|---|---|
| Implant | Autologous | p | Implant | Autologous | p | |
| No. patients | 600 | 317 | 994 | 214 | ||
| Age | 52.5 (10.3) | 52.7 (8.9) | 0.746 | 45.9 (9.7) | 49.8 (8.0) | <.001 |
| BMI | 26.2 (5.3) | 28.3 (5.2) | <.001 | 25.3 (5.3) | 30.0 (5.9) | <.001 |
| Indication for mastectomy | ||||||
| Therapeutic | 575 (95.8%) | 309 (97.5%) | 0.204 | 835 (84.0%) | 166 (77.6%) | 0.024 |
| Prophylactic | 25 (4.2%) | 8 (2.5%) | 159 (16.0%) | 48 (22.4%) | ||
| Mastectomy type | ||||||
| Nipple sparing | 70 (11.7%) | 8 (2.5%) | <.001 | 216 (21.7%) | 8 (3.7%) | <.001 |
| Simple or modified radical | 530 (88.3%) | 309 (97.5%) | 778 (78.3%) | 206 (96.3%) | ||
| Lymph node biopsy | ||||||
| SLNB | 301 (50.2%) | 189 (59.6%) | <.001 | 474 (47.7%) | 96 (44.9%) | <.001 |
| ALND | 216 (36.0%) | 73 (23.0%) | 276 (27.8%) | 29 (13.6%) | ||
| None | 83 (13.8%) | 55 (17.4%) | 244 (24.5%) | 89 (41.6%) | ||
| Smoking status | ||||||
| None smoker | 393 (66.3%) | 189 (59.6%) | 0.085 | 674 (68.6%) | 118 (55.7%) | 0.001 |
| Previous smoker | 187 (31.5%) | 116 (36.6%) | 285 (29.0%) | 88 (41.5%) | ||
| Current smoker | 13 (2.2%) | 12 (3.8%) | 24 (2.4%) | 6 (2.8%) | ||
| Diabetes | ||||||
| Yes | 26 (4.3%) | 24 (7.6%) | 0.040 | 20 (2.0%) | 10 (4.7%) | 0.023 |
| No | 574 (95.7%) | 293 (92.4%) | 974 (98.0%) | 204 (95.3%) | ||
| Radiation | ||||||
| Before reconstruction | 24 (4.0%) | 53 (16.7%) | <.001 | 60 (6.0%) | 37 (17.3%) | <.001 |
| During/after reconstruction | 137 (22.8%) | 86 (27.1%) | 192 (19.3%) | 33 (15.4%) | ||
| None | 439 (73.2%) | 178 (56.2%) | 742 (74.6%) | 144 (67.3%) | ||
| Chemotherapy | ||||||
| During/after reconstruction | 210 (35.0%) | 120 (37.9%) | 0.392 | 312 (31.4%) | 52 (24.3%) | 0.040 |
| Not during/after reconstruction | 390 (65.0%) | 197 (62.1%) | 682 (68.6%) | 162 (75.7%) | ||