Table 3.
Multivariable Analysis on Factors Associated with Two-Year Postoperative Complication for Unilateral Reconstruction Patients
| Variable | Overall complication |
Major complication |
Failure1 |
||||||
|---|---|---|---|---|---|---|---|---|---|
| OR | 95% CI | p | OR | 95% CI | p | OR | 95% CI | p | |
| Age | 1.02 | (1.01, 1.04) | 0.003 | 1.02 | (1.00, 1.04) | 0.021 | 1.02 | (0.98, 1.05) | 0.358 |
| BMI | 1.05 | (1.02, 1.08) | <.001 | 1.06 | (1.03, 1.09) | 0.001 | 1.08 | (1.02, 1.14) | 0.009 |
| Procedure type | |||||||||
| Implant | -Reference- | -Reference- | -Reference- | ||||||
| Autologous | 2.50 | (1.66, 3.77) | <.001 | 2.19 | (1.39, 3.47) | 0.001 | 0.12 | (0.04, 0.36) | <.001 |
| Mastectomy type | |||||||||
| Simple or modified radical | -Reference- | -Reference- | -Reference- | ||||||
| Nipple sparing | 1.81 | (1.02, 3.20) | 0.042 | 1.63 | (0.85, 3.14) | 0.142 | 3.36 | (1.27, 8.93) | 0.015 |
| Indication for mastectomy | |||||||||
| Therapeutic | -Reference- | -Reference- | -Reference- | ||||||
| Prophylactic | 0.96 | (0.38, 2.41) | 0.928 | 1.15 | (0.41, 3.18) | 0.789 | - | - | - |
| Lymph node biopsy | |||||||||
| None | -Reference- | -Reference- | -Reference- | ||||||
| SLNB | 0.78 | (0.49, 1.25) | 0.305 | 0.85 | (0.49, 1.45) | 0.543 | 0.70 | (0.24, 2.08) | 0.519 |
| ALND | 0.90 | (0.52, 1.56) | 0.704 | 1.02 | (0.55, 1.91) | 0.944 | 1.14 | (0.38, 3.46) | 0.817 |
| Smoking status | |||||||||
| Non smoker | -Reference- | -Reference- | -Reference- | ||||||
| Previous smoker | 1.01 | (0.73, 1.39) | 0.955 | 1.04 | (0.73, 1.50) | 0.814 | 1.37 | (0.68, 2.77) | 0.379 |
| Current smoker | 2.77 | (1.18, 6.53) | 0.020 | 1.98 | (0.78, 5.01) | 0.148 | 6.70 | (1.77, 25.31) | 0.005 |
| Diabetes | |||||||||
| No | -Reference- | -Reference- | -Reference- | ||||||
| Yes | 0.94 | (0.49, 1.83) | 0.863 | 1.17 | (0.58, 2.35) | 0.659 | 1.97 | (0.63, 6.17) | 0.246 |
| Radiation | |||||||||
| None | -Reference- | -Reference- | -Reference- | ||||||
| Before reconstruction | 1.15 | (0.66, 1.99) | 0.621 | 1.12 | (0.60, 2.08) | 0.729 | 2.86 | (0.76, 10.73) | 0.119 |
| During/after reconstruction | 1.63 | (1.06, 2.48) | 0.025 | 1.86 | (1.16, 2.97) | 0.009 | 3.40 | (1.53, 7.57) | 0.003 |
| Chemotherapy | |||||||||
| Not during/after reconstruction | -Reference- | -Reference- | -Reference- | ||||||
| During/after reconstruction | 1.12 | (0.78, 1.60) | 0.547 | 1.32 | (0.88, 1.97) | 0.181 | 1.70 | (0.79, 3.66) | 0.176 |
1.
For the sake of model convergence, indication for mastectomy was not included as a predictor for the model on failure.