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. 2019 May 22;10:1106. doi: 10.3389/fimmu.2019.01106

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Copyright © 2019 Lu, Wang, Liu, Zhang, Lu, Li, Chen, Nie and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Protein sequence analysis of the CIITA. (A) NACHT domains and LLR domains of human and grass carp CIITA were identified with Smart BLAST in NCBI (https://www.ncbi.nlm.nih.gov/). (B) GTP-binding motifs and NLS were identified by the characteristic sequence analysis reported in human. The accession numbers of CIITA included in amino acid sequence alignment are as follows: Homo sapiens, NP_001273331; Chelonia mydas, XP_007058212; Xenopus tropicalis, XP_017952759; Ictalurus punctatus, AFL70283; Danio rerio, XP_009297712; Ctenopharyngodon idella, AXY05349.