Figure 2.
Representative images of patients that underwent 18F-FDG PET/CT for lung cancer staging. Axial PET/CT images (A, B) show FDG-avid intrapulmonary lesions. Histopathology confirmed an adenocarcinoma in (A) and squamous cell carcinoma in (B). Corresponding SUVmax are presented (C and D) for OSEMTOF, OSEMPSF, BSREM350, BSREM450, BSREM600, BSREM800, and BSREM1200. While the absolute increase of SUVmax using BSREM compared to OSEM is similar in both cases, the relative increase is more pronounced in the patient with adenocarcinoma. 18F-FDG, 18F-fludeoxyglucose; BSREM, block sequential regularized expectation maximization; OSEM, ordered subset expectation maximization; SUVmax, maximum standardized uptake value.