Table 3.
Absolute and relative SUVmax differences among OSEM and BSREM reconstructions of lung cancers
| Adenocarcinoma, n = 34 | Squamous cell carcinoma, n = 24 | p-value a | ||
| Absolute ΔSUVmax | BSREM350 to OSEMTOF | +2.9±1.6 | +4.0±2.9 | 0.403 |
| BSREM450 to OSEMTOF | +2.4±1.5 | +3.4±2.5 | 0.324 | |
| BSREM600 to OSEMTOF | +1.9±1.4 | +2.8±2.1 | 0.132 | |
| BSREM800 to OSEMTOF | +1.4±1.3 | +2.1±1.6 | 0.029 | |
| BSREM1200 to OSEMTOF | +0.8±1.0 | +1.2±1.0 | 0.077 | |
| Relative ΔSUVmax | BSREM350 to OSEMTOF | +34.8±20.5% | +23.4%±7.7 | 0.048 |
| BSREM450 to OSEMTOF | +28.8±18.4% | +19.7%±6.2 | 0.072 | |
| BSREM600 to OSEMTOF | +22.6±16.7% | +16.2%±5.1 | 0.276 | |
| BSREM800 to OSEMTOF | +16.2±14.9% | +12.6%±4.2 | 0.728 | |
| BSREM1200 to OSEMTOF | +9.7±11.7% | +7.3%±3.4 | 0.528 | |
| Absolute ΔSUVmax | BSREM350 to OSEMPSF | +2.2±1.2 | +2.9±2.3 | 0.788 |
| BSREM450 to OSEMPSF | +1.7±1.1 | +2.2±1.9 | 0.597 | |
| BSREM600 to OSEMPSF | +1.2±1.0 | +1.7±1.5 | 0.269 | |
| BSREM800 to OSEMPSF | +0.7±0.8 | +1.0±1.0 | 0.136 | |
| BSREM1200 to OSEMPSF | +0.1±0.7 | +0.1±0.5 | 0.868 | |
| Relative ΔSUVmax | BSREM350 to OSEMPSF | +24.4±13.8% | +15.6%±5.6 | 0.012 |
| BSREM450 to OSEMPSF | +18.9±11.7% | +12.1%±4.1 | 0.021 | |
| BSREM600 to OSEMPSF | +13.2±10.1% | +8.8%±3.3 | 0.172 | |
| BSREM800 to OSEMPSF | +7.3±8.7% | +5.4%±2.7 | 0.850 | |
| BSREM1200 to OSEMPSF | +1.4±6.7% | +0.5%±2.7 | 0.425 |
BSREM, block sequential regularized expectation maximization; OSEM, ordered subset expectation maximization; PSF, point spread function modelling; SUVmax, maximum standardized uptake value; TOF, time of flight.
Values are given as mean ± standard deviation.
a
Mann–Whitney U test