Table 2.

Fold changes of DEGs (Differentially expressed genes) upregulated upon HIV‐1 exposure on cervical tissues compared to tissues exposed to media control

Sample number	CXCL10	SAA1/SAA2	MUC1	IL36A	FMO2	IL8	WARS
E‐8776 (HIV)	11.16	8.75	6.54	3.29	5.06	3.51	4
E‐7688 (HIV)	40.22	2.22	2.83	0.99	2.6	1.56	9.45
E‐8901 (HIV)	5.7	0.72	1.32	0.84	0.8	0.99	1.51
E‐8916 (HIV)	19.7	16	580.04	235.57	34.06	34.78	5.31
E‐9274 (HIV)	12.64	4.11	3.76	2.95	3.41	5.39	9.45
E‐9301 (HIV)	1.41	0.26	0.37	1.41	0.79	2.16	1.03
E‐9323 (HIV)	9.19	4.06	2.57	1.61	1.3	0.75	3.66
E‐9387 (HIV)	15.67	1.57	0.79	0.58	1.09	1.42	1.69
E‐9483 (HIV)	3.56	0.93	1.75	2.53	2.19	2.19	2.11
E‐9493 (HIV)	2.51	1.2	0.68	1.57	1.59	1.12	1.69
E‐9564 (HIV)	15.24	1.8	10.27	NA	9.65	3.16	10.34
E‐9571 (HIV)	2.57	0.2	1.04	0.38	0.47	0.29	1.09
E‐9769 (HIV)	7.26	0.74	0.18	2.04	0.8	0.26	0.33
E‐9864 (HIV)	13.27	1.21	5.39	NA	8.51	1.79	11.16
Average fold change (n = 14)	11.44a	3.13	44.11a	21.15a	5.17a	4.24a	4.49a
P value	0.0001	0.104	0.0245	0.05	0.0157	0.0245	0.0009

The upregulated genes found in the transcriptome analysis was verified using RT‐PCR on additional tissues (n = 14). Numbers denote fold changes of DEGs in tissues exposed to HIV‐1 compared to tissues exposed to media control.

^aSix genes out of the seven genes were found to be statistically upregulated by RT‐PCR. A non‐parametric paired t test was used for calculating the statistical significance.