Table 2.
Patient characteristics after PS matching (HMA users post approval, N=225; and all CMML patients pre approval, N=395). HMA, Hypomethylating agents; ESA, Erythropoiesis-stimulating agent; RBC, Red blood cell.
| All before 2004 | HMA users after 2006 | P-value | Standardized Difference | |
|---|---|---|---|---|
| Total N | 395 | 225 | 8.79 | |
| Age Group | 0.31 | |||
| 66–69 | 12.9% | 17.8% | 13.53 | |
| 70–74 | 23.3% | 21.8% | −3.62 | |
| 75–79 | 27.6% | 23.1% | −10.32 | |
| 80+ | 36.2% | 37.3% | 2.35 | |
| Sex | .75 | |||
| Female | 35.9% | 34.7% | −2.68 | |
| Male | 64.1% | 65.3% | 2.68 | |
| Race | .93 | |||
| White | 90.9% | 90.7% | −0.76 | |
| Other | 9.1% | 9.3% | 0.76 | |
| Hispanic | .36 | |||
| Non-Hispanic | 97.0% | >95.1% | 9.77 | |
| Hispanic | 3.0% | <4.9% | −9.77 | |
| Marital Status | .19 | |||
| Married | 60.3% | 57.8% | −5.03 | |
| Unmarried | 32.2% | 30.2% | −4.17 | |
| Other | 7.6% | 12.0% | 14.86 | |
| Percent adults 25+ with <= High school education | .79 | |||
| <33% | 28.6% | 26.2% | −5.35 | |
| 33%−66% | 57.0% | 59.6% | 5.26 | |
| ≥ 66% | 14.4% | 14.2% | −0.59 | |
| Median Household Income | .58 | |||
| <$33,000 | 20.0% | 18.2% | −4.52 | |
| $33,000–40,000 | 17.5% | 15.1% | −6.39 | |
| $40,000–50,000 | 18.5% | 22.7% | 10.37 | |
| ≥ $50,000 | 44.1% | 44.0% | −0.10 | |
| Metro Residency | .34 | |||
| Metro | 79.5% | 82.7% | 8.11 | |
| Non-metro | 20.5% | 17.3% | −8.11 | |
| Medicaid Dual Eligibility | .15 | |||
| No | 94.2% | 91.1% | −11.77 | |
| Yes | 5.8% | 8.9% | 11.77 | |
| Elixhauser Comorbidity Index | .092 | |||
| None | 41.3% | 35.6% | −11.76 | |
| 1 to 2 | 39.0% | 37.3% | −3.41 | |
| more than 3 | 19.7% | 27.1% | 17.45 | |
| Disability | .46 | |||
| Not disabled | 95.9% | 94.7% | −6.07 | |
| Disabled | 4.1% | 5.3% | 6.07 | |
| Hospitalization for infection or bleeding | .46 | |||
| No | 83.5% | 85.8% | 6.20 | |
| Yes | 16.5% | 14.2% | −6.20 | |
| RBC transfusion | .78 | |||
| Naïve | 94.2% | 92.9% | 5.29 | |
| User | >3.0% | <4.9% | −9.77 | |
| Dependent | <2.8% | <4.9% | −10.93 | |
| Prior Platelet transfusion | .61 | |||
| No | >97.2% | >95.1% | 10.93 | |
| Yes | <2.8% | <4.9% | −10.93 |
*
Abbreviations: HMA, Hypomethylating agents; ESA, Erythropoiesis-stimulating agent; RBC, Red blood cell. Values with < or > are suppressed according to our data use agreement not reveal cell sizes <11. Standardized differences reflect values shown in table if a value is suppressed.