Figure 2. Genes regulated by super-enhancers harbor H3K4me3 broad domains in hippocampal neurons.
A) Boxplot of RNA expression levels for a control gene set, E-reg genes, and SE-reg genes. Control peaks were a set of genes of the same number as the E-reg gene set that was randomly selected from genes that were not part of the E-reg or SE-reg gene sets. B) Density plot showing the distribution of H3K4me3 breadth values for control genes, E-reg genes, and SE-reg genes. * = p < 0.05, ** = p < 0.01, *** = p < 1e-10 by Wilcoxon rank sum with Bonferroni correction.
