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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: J Nucl Cardiol. 2018 Dec 19;26(1):158–173. doi: 10.1007/s12350-018-01552-4

Figure 2.

Figure 2.

99mTc-MDP and 99mTc-PYP images in cardiac ATTR amyloidosis. Images of an 86-year-old man with prostate cancer and a 99mTc-MDP scan showing no myocardial radiotracer uptake. He presented a month later with heart failure, and echocardiography revealed classic features of cardiac amyloidosis. A clonal abnormality was excluded by serum and urine immunofixation, and serum-free light chain levels. A 99mTc-PYP scan was performed using chest planar and SPECT imaging 2.5 hours after injection of radiotracer; Grade 3 myocardial uptake on 99mTc-PYP planar, and SPECT with a heart-to-contralateral ratio of 1.42 on planar images (≥ 1.3 abnormal for late images) diagnosed cardiac ATTR amyloidosis.