Figure 2.

Summary of our in-house developed MABIS algorithm. A pre-processing step is completed before every atlas in the atlas database (1,2, …, N atlases) is deformed to the unsegmented mouse (in this example in the cranial body region). At the organ level, the atlases with the highest NCC coefficients are selected. The STAPLE filter algorithm calculates a consensus contour (thick contour) from the individual deformed mouse contours (thin lines) and the post-processing algorithm is executed in a last step (the right image is rotated 90 degrees for viewing purposes). MABIS, multiatlas-based image segmentation; NCC, normalized cross-correlation; STAPLE, Simultaneous Truth And Performance Level Estimation.