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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Cancer Res. 2018 Nov 1;79(1):231–241. doi: 10.1158/0008-5472.CAN-18-1089

Figure 4. Effects of intronic variants on luciferase activity.

Figure 4

A) VEGFA rs1885657 C, rs58159269 C, rs943070 G, and a “triple variant” construct (C/C/G). B) VEGFA rs3024987 T. C) WWOX rs77533819 C, rs8047917 A, rs7190335 C, and a “triple variant” construct (C/A/C). D) ITGAV rs3816375 G. Luciferase activity was tested in Caki-1, TIME and LPEC lines (from left to right). The mean±SEM of luciferase activity of the experiments, conducted in quadruplicate (n=12 for each construct), is shown. *P<0.05, **P<0.01, ***P<0.001.