Fig. 2.

As a validation and test of the genomic array being used for the larger prospective study, the intersubject variation and intracohort variation (healthy controls or traumatically injured patients) had to be determined. a Similar levels of transcriptomic variation among healthy subjects versus among trauma patients, but more than the variance within healthy subjects. Principle component (b) and hierarchical cluster (c) analyses on leukocyte gene expression from 14 trauma and 17 healthy subjects demonstrating that the genomic signatures of the individuals within either healthy controls or trauma patients “cluster” close as a group but can be separated based on cohort characteristics (control vs. injured patients) (figure adapted from Cobb et al. [28])