Table 2.

Spearman correlation (p values) between the difference from reference score (DFR) calculated for the entire genome and for gene ontologies participating in the inflammatory response with injury severity and the development of organ failure (adapted from [3,8])

Gene ontologies	Probe sets	Severity of physiologic abnormality based on the APACHE score	Severity of injury based on the ISS score	Degree of organ failure based on the Marshall score	Degree of organ failure after controling for the score APACHE and ISS
Entire genome	50,874	0.2944 (0.0002)	0.2664 (0.0007)	0.3009 (0.0001)	0.1875 (0.0191)
Antioxidant	494	0.3212 (<0.0001)	0.1018 (0.2062)	0.2460 (0.0018)	0.1523 (0.0576)
Chemokine	887	0.2954 (0.0002)	0.2547 (0.0012)	0.3444 (<0.0001)	0.2403 (0.0025)
Coagulation	392	0.3164 (<0.0001)	0.1899 (0.0169)	0.3381 (<0.0001)	0.2403 (0.0025)
Cytokines	2,400	0.3245 (<0.0001)	0.1691 (0.0337)	0.3357 (<0.0001)	0.2393 (0.0026)
Heat shock	263	0.1914 (0.0160)	0.1994 (0.0120)	0.2043 (0.0100)	0.1218 (0.1299)
HMGB1	130	0.1315 (0.0995)	0.1362 (0.0880)	0.1914 (0.0160)	0.1393 (0.0828)
TLR (toll-like receptors)	17	−0.0554 (0.4381)	−0.0087 (0.9134)	0.0450 (0.5745)	0.0693 (0.3900)