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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2018 Aug 29;27(12):1491–1499. doi: 10.1158/1055-9965.EPI-17-0813

Table 5.

Relative shift in geometric mean (95% CI) percent fibroglandular volume between tertiles of MEP concentrations stratified by Tanner stage at EDC measurementa

EDC Tanner
Stage		 Overall Testb
(p-value)		 Middle vs
Lowest Tertile (ref)		 Highest vs
Lowest Tertile (ref)		 Highest vs
Middle Tertile (ref)		 Trendb
(p-value)
MEP
B1 0.742 1.03 (0.94, 1.12) 1.00 (0.91, 1.09) 0.97 (0.89, 1.06) 0.875
B4 0.026* 0.99 (0.91, 1.07) 1.10* (1.01, 1.20) 1.12* (1.02, 1.22) 0.024*
a

Estimating Tanner stage-specific association between EDC metabolite and percent fibroglandular volume using a multivariable GEE model adjusting for age at B1 EDC measurement, age at B4 EDC measurement, BMI z-score at B1, BMI z-score at B4, and maternal education, including an interaction between EDC tertile and Tanner stage; restricted to subset of association for which the interaction with Tanner stage was significant (p<0.05)

b

bOverall test whether EDC category improves model fit (Likelihood ratio test)

c

Trend evaluated by modeling the log(median) concentration within tertiles as a continuous variable

*

p<0.05,

**p<0.01,

***p<0.001