Figure 1.

Dexamethasone treatment reduces fetal number and litter size at E17.5 without affecting either at E15.5. Dexamethasone (Dex, stippled bars: 100 µg/kg/day) or vehicle (Veh, white bars) was administered to pregnant dams in their drinking water from E12.5 to E15.5. Individual data points represent mean values per litter. Data are means ± s.e.m. and were analysed by Student’s t-test (A and C) or two-way ANOVA with post hoc Tukey tests (B and D). Significant effect of treatment, *P < 0.05, **P < 0.01; significant effect of genotype, ^#P < 0.05, n = 12–13 litters per group.