Figure 2.

Dexamethasone transiently reduces the mitral deceleration index, dependent on GR. Dexamethasone (100 µg/kg/day; stippled bars) or vehicle (Veh, white bars) was administered to pregnant dams from E12.5 to E15.5. Mitral deceleration index (MDI) was measured by in vivo ultrasound imaging at (A) E15.5 and (B) E17.5. Data are means ± s.e.m. and were analysed by two-way ANOVA with post hoc Tukey tests: significant effect of treatment, *P < 0.05; significant effect of genotype, ^#P < 0.05, n = 8–28 fetuses from 5 to 6 litters per group.