Table 4. Genotypes of the F1 CMAH KO piglets used for PEDV challenge.
| Exp. | Sow/ L667- | Genotype | Site I of Mutant allele | |||
|---|---|---|---|---|---|---|
| Parity | ID. | Litter size | D/D | D/M | ||
| 1 | 1 | 10 | 12 | 1 | 0 | - |
| 11 | 6 | 2 | 0 | - | ||
| 12 | 13 | 3 | 0 | - | ||
| Control | 12 | 1 | 0 | - | ||
| 2 | 2 | 10 | 8 | 3 | 0 | - |
| 11 | 6 | 3 | 1 | +1 | ||
| 12 | 13 | 2 | 0 | - | ||
| Control | 12 | 1 | 0 | - | ||
| 3 | 3 | 10 | 12 | 4 | 2 | -14 |
| 11 | 1 | 0 | 0 | - | ||
| 12 | 12 | 5 | 1 | -2 | ||
| Control | 10 | 1 | 0 | - | ||
Note: Genotypes: D indicates that the mutation occurred at two sites simultaneously and resulted in a 161-bp deletion, whereas M is site I-mutated, on codon region and null CMAH expression; D/D refers to the case in which the 161-bp deletion occurred on both chromosomes. The controls are wild-type piglets.