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HKIR+/+/Vκ10 and HKIR+/+ mice contain elevated levels of λ-expressing B cells. Spleen cells from mice of the indicated genotypes were stained with anti-λ Abs and analyzed by flow cytometry. Gates are set on the λ+ subpopulations and the percentages of these cells of total splenocytes are indicated. The few λ+ B cells present in HKIR+/− mice mainly express the nontransgenic Igh (IgMb) allele (data not shown). The data were derived from at least three mice of each genotype.
