. Author manuscript; available in PMC: 2019 May 29.

Published in final edited form as: Psychosom Med. 2016 Nov-Dec;78(9):979–990. doi: 10.1097/PSY.0000000000000410

Table 4.

Interaction of prenatal depression group and placental SLC6A4 gene expression for AUC¹ cortisol at one month for the overall sample (n=103) and stratified by daughters (n=50) and sons (n=53).²

	All			Daughters			Sons
Predictor variables	β	SE	P	β	SE	p	β	SE	p
AUC Cortisol^1,3
Intercept	2.67	.37	<.001	3.16	.60	<.001	2.47	.45	<.001
Time since feeding (min) ³	.12	.09	.21	.04	.15	.79	.15	.12	.20
Education⁴	−.36	.16	.02	−.23	.25	.36	−.54	.20	.01
Control vs. Prenatal MDD⁵	−.16	.16	.33	−.43	.25	.09	−.02	.21	.93
Preconception-only MDD vs. Prenatal MDD⁵	−.34	.19	.08	−.52	.29	.08	−.23	.26	.36
SLC6A4 Gene Expression³	−.13	.12	.29	−.03	.23	.90	−.16	.13	.24
[Control vs. Prenatal MDD⁵] * SLC6A4	.26	.18	.14	−.17	.30	.57	.61	.22	.007
[Preconception vs. Prenatal MDD⁵] * SLC6A4	.18	.23	.44	.06	.42	.89	.31	.27	.26

AUC=Area Under the Curve;

Per group cell sizes for the overall sample were n’s=45, 23, 35 for Prenatal MDD, Preconception-only MDD, and Control, respectively; per group cell sizes for daughters were n’s =17, 13, and 20, respectively; per group cell sizes for sons were n’s=28, 10, and 15. Unstandardized regression coefficients are presented.

Natural log transformed;

⁴

≤ high school degree vs. > high school degree;

⁵

MDD=major depressive disorder; contrasts are based on categorical MDD groups.