Table 1.
Preoperative demographics and comorbidities
| MELD <9 | MELD 9–15 | MELD >15 | p-value | |
|---|---|---|---|---|
| Baseline Characteristics | (n=15566) | (n=4542) | (n=1164) | |
| Age (y, median, IQR) | 65 (57–72) | 69 (62–76) | 65 (57–73) | <0.0001 |
| Female | 4905 (31.5%) | 930 (20.5%) | 342 (29.4%) | <0.0001 |
| Chronic lung disease (mod/sev) | 1586 (10.5%) | 624 (14.1%) | 250 (22.1%) | <0.0001 |
| Prior stroke | 1133 (7.3%) | 483 (10.7%) | 174 (15.0%) | <0.0001 |
| Diabetes | 6250 (40.2%) | 2164 (47.7%) | 717 (61.6%) | <0.0001 |
| Dialysis dependent renal failure | 0 (0.0%) | 0 (0.0%) | 593 (51.0%) | <0.0001 |
| Hypertension | 12851 (82.6%) | 4000 (88.1%) | 1080 (92.8%) | <0.0001 |
| Coronary artery disease | 12983 (84.2%) | 3775 (84.1%) | 961 (84.4%) | 0.9838 |
| Heart failure within 2 weeks | 3729 (24.0%) | 1818 (40.1) | 632 (54.4%) | <0.0001 |
| Ejection Fraction (median, IQR) | 55 (50–60) | 55 (40–60) | 50(37–60) | <0.0001 |
| Active endocarditis | 132 (0.9%) | 91 (2.0%) | 69 (6.0%) | <0.0001 |
| STS PROM (%; median, IQR) | 1.8% ± 2.5 | 3.8% ± 4.8 | 9.3% ± 10.2 | <0.0001 |
| Liver disease | 546 (3.5%) | 245 (5.4%) | 90 (7.8%) | <0.0001 |
| MELD (median, IQR) | 7 (6.4–7.5) | 10.6 (9.6–12.0) | 19.7 (17.5–20.8) | <0.0001 |
| Creatinine (median, IQR) | 0.9 (0.8–1.0) | 1.3 (1.1–1.5) | 3.2 (1.9–5.9) | <0.0001 |
| T otal bilirubin (median, IQR) | 0.5 (0.4–0.7) | 0.6 (0.4–0.9) | 0.5 (0.3–0.8) | <0.0001 |
| INR (median, IQR) | 1.0 (1.0–1.1) | 1.1 (1.0–1.2) | 1.1 (1.0–1.4) | <0.0001 |
INR = International Normalized Ratio; MELD = Model for End-stage Liver Disease; PROM = Predicted Risk of Mortality; STS = Society of Thoracic Surgeons