Fig 1.

Opioid use pre- and post-HSCT by AAPT pain categories. *3 patients in acute episodic pain group had not reported using opioids. **1 patient in acute episodic pain group was on long acting opioids intermittently. AAPT, ACTTION-American Pain Society Pain Taxonomy diagnostic criteria for chronic SCD pain; AAPT subtype 1, Chronic SCD pain without contributory disease complications was used if there was no evidence of contributory SCD complications based on either clinical signs (e.g., presence of leg ulcers) or test results (e.g., imaging abnormalities); AAPT subtype 2, Chronic SCD pain with contributory disease complications was used if there was evidence of contributory SCD complications based on clinical signs or test results; AAPT subtype 3, Chronic SCD pain with mixed pain types was used if there was evidence of contributory SCD complications (e.g., avascular necrosis) based on clinical signs or test results and there was also pain occurring in unrelated sites (e.g., arms, back, chest, or abdominal pain); HSCT, hematopoietic stem cell transplant; LA Opioids, Long acting opioids; SA Opioids, Short acting opioids; SCD, sickle cell disease.