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Histograms showing no differences in pS422, AT8, TauC3, MC1 and Alz50 positive NFT mean numbers either in the caudate or putamen between the two DS groups (Mann-Whitney rank sum test, p > 0.05), while pS422-ir NFTs numbers were significantly higher compared to TauC3-ir NFTs in the putamen, but not in the caudate, in both, demented (#, Kruskal-Wallis rank sum test, p=0.013) and non-demented (#, Kruskal-Wallis rank sum test, p=0.030) individuals with DS.
