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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Psychol Med. 2018 Nov 29;49(14):2441–2451. doi: 10.1017/S0033291718003446

Table 2.

Associations between mean activation in R NAcc and Putamen and reward-related ESM measures (controlled for age and gender, and the ESM analyses also for overall time of measurement, time of measurement within the day)


L NAcc L Putamen R NAcc R Putamen

Symptom measure beta (se) P beta (se) P beta (se) P beta (se) P

MADRS −.003 (.009) .750 −.001 (.008) .816 −.011 (.010) .268 −.009 (.008) .267
IDS-SR −.012 (.006) .037 −.007 (.005) .177 −.017 (.006) .010* −.013 (.005) .009*

beta(seML) - beta(seML) - beta(seML) - beta(seML) -
ESM measure (serob) pML prob (serob) pML prob (serob) pML prob (serob) pML prob

.039 (.153) - .799 .832 −.095 (.177) - .594 .550 .107 (.143) - .453 .547 .128 (.170) - .451 .421
Reward anticipation (.183) (.158) (178) (159)
.070 (.107) - .512 .548 .015 (.124) - .903 .905 .114 (.100) - .254 .315 .188 (.118) - .110 .076
Activity pleasantness (.117) (.127) (.114) (.106)

.031 (.012) - .010* .016* .019 (.015) - .205 .257 .026 (.010) - .011* .016* .047 (.012) - <.001* .001*
qua (.013) (.017) (011) (015)
Activity pleasantness (t) .025 (.026) - .326 .340 .009 (.030) - .753 .773 .033 (.022) - .138 .166 .004 (.028) - .876 .900
←Reward anticipation (t-1) lin (.026) (.033) (.024) (.035)

Note. All ESM predictors were person-mean-centered. Models with time-varying predictors include random slopes of those predictors (incl. quadratic variables). Models with lagged predictors include the lagged outcome as a predictor. Abbreviations: L=left, R=right, NAcc=Nuccleus Accumbens, MADRS= Montgomery-Asberg Depression Scale, IDS-SR=Inventory of Depressive Symptomatology - Self-Report, se=standard error, p=p-value, seML= standard error estimated using standard log likelihood procedure, serob=standard error estimated using the robust Huber-White sandwich estimation procedure, pML=p-value of effect based on the log-likelihood standard error estimation, prob=p-value of effect based on robust Huber-White sandwich estimation, qua=quadratic (referring to time-lagged quadratic effect of reward anticipation on activity pleasantness, lin=linear (referring to time-lagged linear effect of reward anticipation on activity pleasantness).

*

indicates a significant p-value after correction for multiple testing following the Holm method (Aickin and Gensler, 1996, Holm, 1979), correction performed within each row of the table.