Table 2:
Association between Uranium Mining Exposure and Hypertension, N= 7,215; 1989–2016; MiDUS cohort.
| Cardiovascular Outcomes |
Uranium Miners N=3151 N (%) |
Non-Uranium Miners N =4064 N (%) |
Unadjusted model O.R. (95% C.I.) |
Multivariable model 1Note 1 O.R. (95% C.I.) |
Multivariable model 2Note 1 O.R. (95% C.I.) |
|---|---|---|---|---|---|
| Self-reported Hypertension | 1099 (44.4%) | 1254 (33.6%) | 1.58 (1.42, 1.75) |
1.43 (1.24, 1.66) |
1.42 (1.22, 1.65) |
| Measured Hypertension | 1339 (43.3%) | 1329 (33.5%) | 1.51 (1.37, 1.67) |
0.85 (0.74, 0.97) |
0.88 (0.77, 1.02) |
| Hypertensive urgency | 17 (0.5%) | 21 (0.5%) | 1.04 (0.55, 1.97) |
0.53 (0.20, 1.38) |
0.51 (0.19, 1.37) |
Note 1: Multivariable analysis model 1 was adjusted for age, sex, race/ethnicity, diabetes mellitus, BMI, current smoking status, current snuff use status, current alcohol use status, and duration of total mining tenure. Model 2 additionally adjusted for absolute FEV1 as a covariate. The missing data for total mining tenure is included in order to keep sample size among analyses consistent.