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. 2019 May 29;9:7995. doi: 10.1038/s41598-019-44475-x

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effect of CoQ₁₀ on Ki67 expression during Tac-induced islet injury. Representative images (a) and quantification (b) of double immunohistochemistry for Ki67 (gray color, marker for cell proliferation) and insulin (red fluorescence, marker for beta cells) in tissue sections from rats. Yellow dotted circles indicate Ki67-positive cells. Scale bar = 20 µm (all panels). Data are presented as the mean ± SE (n = 8). One-way ANOVA was used to analyze the data. ^&P < 0.05 versus the Vh group; ^$P < 0.05 versus the CoQ₁₀ groups; ^#P < 0.05 versus the Tac group.