Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 May 29;9:8002. doi: 10.1038/s41598-019-44513-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Indian patients with PTB exhibit increased molecular degree of perturbation than Chinese independent of disease extension status. PTB patients from both countries were stratified based on lung disease extension using smear acid-fast bacilli (AFB) status (negative or positive) and radiographic distribution of lung lesions (unilateral or bilateral). (A) Hierarchical cluster analysis (Ward’s method with 100X bootstrap) was employed to illustrate the overall expression profile of the biomarkers in PTB patients stratified per AFB smear status and lung disease extension. Dendrograms represent Euclidean distance. (B,C) Left panels: Histograms show the single sample molecular degree of perturbation (MDP) score values in the subgroups of PTB patients. Right panels: Scatter plots of the summary data for each country are shown. (D) MDP score values were also compared between the subgroups of PTB patients between India and China. Lines in the scatter plots represent median values. Data were compared using the Mann–Whitney U test.