Table 2.

Clinical Presentation and Outcomes for 11 Patients With Klebsiella pneumoniae Carbapenemase-producing Klebsiella pneumoniae Bloodstream Infection

ID	Sex	Age	Reason for Hospitalization	Comorbidity	Hospital Event Preceding or Concurrent With KPC-Kp BSI	At the Time of First KPC-Kp BSI					Disposition
						Clinical Symptoms	Central Venous Catheter		Other Device	Immunosuppressants
							Type	Location
1	F	73	Recent pneumonia, transferred to continue care	Hypothyroidism, A fib, PVD, Pressure ulcer	Clostridium difficile infection	Abdominal distention, fever	PICC	Upper extremity	Tracheostomy tube, mechanical ventilator, gastrostomy tube, urinary catheter	…	Transfer to ACH
2	M	64	Recent pneumonia, cardiac arrest, transferred to continue care	COPD, pulmonary HTN	Fever followed by small bowel obstruction due to ruptured appendix	Fever	CVC	Subclavian	Tracheostomy tube, mechanical ventilator, gastrostomy tube	…	Transfer to ACH
3	F	81	Recent right groin infected hematoma around arteriovenous fistula, transferred to continue care	COPD, chronic myelogenous leukemia, ESRD on HD	General deterioration	None documented	Long-term HD catheter	Groin	Tracheostomy tube, mechanical ventilator	Glucocorticoids	Deceased
4	M	62	Recent pneumonia, transferred to continue care	COPD, DM, PVD, HTN, CHF	Septic shock during hemodialysis	Shock	Long-term HD catheter	Subclavian	Tracheostomy tube, mechanical ventilator, gastrostomy tube	…	Deceased
5	F	68	Direct admission for infected PEG tube	Ischemic stroke, MS	Persistent leak around PEG tube despite tube exchange	Fever	…	…	Tracheostomy tube, mechanical ventilator, gastrostomy tube	…	Transfer to ACH
6	F	63	Recent cardiac arrest, transferred to continue care	Asthma, CHF, obesity	Candida endocarditis, pyelonephritis, PEG tube infection	Fever	PICC	Unknown	Tracheostomy tube, mechanical ventilator, gastrostomy tube	…	Transfer to skilled nursing facility
7	F	67	Recent pneumonia, transferred to continue care	Adrenal insufficiency, COPD	Acute kidney injury requiring hemodialysis	Bradycardia	CVC, short-term HD catheter, PICC	Subclavian, internal jugular, lower extremity	Endotracheal tube, mechanical ventilator, gastrostomy tube	Glucocorticoids	Deceased
8	M	56	Recent ischemic stroke, transferred to continue care	HTN, CKD, dilated cardiomyopathy, A Fib	Respiratory failure, intubation	Hypoxia	…	…	Automated implantable cardioverter-defibrillator, gastrostomy tube	Glucocorticoids	Transfer to hospice
9	F	60	Recent left leg abscess, acalculous cholecystitis, transferred to continue care	COPD, CHF, seizure	PEG tube placement complicated by liver injury	Altered mental status, hypotension	CVC	Subclavian	Gastrostomy tube	Glucocorticoids	Transfer to ACH
10	F	73	Recent ischemic stroke, transferred to continue care	CKD, HTN, ESRD on HD, remote history of stomach cancer	Septic shock	Shock, hypoglycemia	Short-term HD catheter, port-catheter	Internal jugular, chest	Gastrostomy tube	…	Deceased
11	M	48	Recent gastrointestinal bleeding from unclear source, transferred to continue care	HTN, DM, right below knee amputation, sacral decubitus ulcer, ESRD on HD	Deep venous thrombosis around PICC line	Fever	Short-term HD catheter, PICC	Internal jugular, upper extremity	…	…	Deceased

Abbreviations: A fib, atrial fibrillation; ACH, acute care hospital; BSI, bloodstream infection; CHF, congestive heart failure; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; CVC, central venous catheter; DM, diabetes mellitus; ESRD, end-stage renal disease; F, female; HD, hemodialysis; HTN, hypertension; KPC-Kp, Klebsiella pneumoniae carbapenemase-producing Klebsiella pneumoniae; M, male; MS, multiple sclerosis; PEG, percutaneous endoscopic gastrostomy; PICC, peripherally inserted central venous catheter; PVD, peripheral vascular disease.