Table 1.
Patient Characteristics According to Antibiotic Use at the Time of Bacteremia
| Characteristic | FQ (n = 26) | Non-FQ or None (n = 29) | P Value |
|---|---|---|---|
| Age, y, median (range)a | 61 (25-72) | 60 (21-78) | >.5 |
| Genderb | |||
| Male | 17 (68) | 17 (63) | >.5 |
| Female | 8 (32) | 10 (27) | |
| Underlying diseaseb | |||
| AML | 16 (64) | 11 (40.7) | >.5c |
| MDS | 0 | 5 (18.5) | |
| ALL | 3 (12) | 6 (22.2) | |
| Other | 6d (24) | 5e (18.5) | |
| ANC ≤ 500/mm3a | |||
| Yes | 23 (88.5) | 15 (51.7) | .004 |
| No | 3 (11.5) | 14 (48.3) | |
| HCTa | |||
| Yes | 12f (46.1) | 17g (58.6) | .4 |
| No | 14 (53.9) | 12 (41.4) | |
Data are presented as n (%) unless otherwise indicated.
Abbreviations: ALL, acute lymphoblastic leukemia; AML, acute myelogenous leukemia; ANC, absolute neutrophil count; FQ, fluoroquinolone; HCT, hematopoietic cell transplant; MDS, myelodysplastic syndrome.
aAll bacteremic events.
bUnique patients per category of antibiotic use at time of bacteremia.
cAML + MDS vs others.
dConsisted of 2 lymphoma, 3 mutiple myeloma, and 1 aplastic anemia cases.
eConsisted of 3 lymphoma and 2 chronic lymphocytic leukemia cases.
fConsisted of 9 allogeneic and 3 autologous cases.
gConsisted of 16 allogeneic and 1 autologous cases.