Table 5.

Genotype distribution and allele frequencies of the VEGF -2578 C/A polymorphism in control and case group

Genotype	Fetus		Mother		Father
VEGF -2578 C/A	Controls N = 100 (%)	Cases N = 100 (%)	Controls N = 100 (%)	Cases N = 100 (%)	Controls N = 100 (%)	Cases N = 100 (%)
CC	38 (38%)	25 (25%)	32 (32%)	35 (35%)	76 (76%)	78 (78%)
CA	48 (48%)	56 (56%)	48 (48%)	50 (50%)	22 (22%)	15 (15%)
AA	14 (14%)	19 (19%)	20 (20%)	15 (15%)	2 (2%)	7 (7%)
C	124 (0.62)	106 (0.53)	112 (0.56)	120 (0.60)	170 (0.85)	174 (0.87)
A	76 (0.38)	94 (0.47)	88 (0.44)	80 (0.40)	30 (0.15)	26 (0.13)
HWE p value	0.03 0.86	1.54 0.21	0.07 0.79	0.17 0.68	0.08 0.77	15.61 < 0.00001**
	OR (95% CI)	p value	OR (95% CI)	p value	OR (95% CI)	p value
CA Vs CC	1.77 (0.94–3.34)	0.06	0.95 (0.51–1.77)	0.87	0.66 (0.32–1.37)	0.26
AA Vs CC	2.06 (0.87–4.85)	0.09	0.68 (0.30–1.56)	0.36	3.41 (0.68–16.94)	0.11
CA + AA Vs CC	1.83 (1.00–3.37)	0.04*	0.87 (0.48–1.57)	0.65	0.89 (0.46–1.72)	0.7
AA Vs CC + CA	0.69 (0.32–1.47)	0.34	1.41 (0.67–2.95)	0.35	0.27 (0.05–1.33)	0.08
CA Vs CC + AA	1.39 (0.77–2.51)	0.1	1.08 (0.60–1.95)	0.9	0.62 (0.28–1.35)	0.2
A Vs C	1.44 (0.97–2.15)	0.06	0.84 (0.57–1.26)	0.41	1.13 (0.64–2.00)	0.66

p value < 0.05* is statistically significant, p value < 0.001**