Table 1.
AC-FET | NC-LPS | P value | |
---|---|---|---|
No. of cycles | 2611 | 8425 | |
Maternal age (year) | 31 (28, 35) | 31 (28, 35) | 0.722 |
BMI (kg/m2) | 21.6(19.9, 23.5) | 21.2 (19.6, 23.1) | < 0.001 |
Basal FSH (miu/ml) | 6.11 (5.1, 7.4) | 6.2 (5.3, 7.4) | 0.005 |
Primary subfertility | 1050 (40.2) | 3500 (41.5) | 0.228 |
Causes of infertility (%) | |||
Teratospermia | 344 (13.2) | 1113 (13.2) | 0.960 |
Oligoasthenozoospermia | 225 (8.6) | 793 (9.4) | 0.220 |
Oviduct factor | 2345 (89.8) | 7524 (89.3) | 0.462 |
Endometrial thickness (mm) on translate day | 10.8 (9.9, 11.7) | 11.4 (10.4, 12.5) | < 0.001 |
Number of transferred embryos (%) | 0.605 | ||
1 | 428 (16.4) | 1313 (15.6) | |
2 | 1997 (76.5) | 6514 (77.3) | |
3 | 186 (7.1) | 598 (7.1) | |
Blastomere or blastocyst transfer (%) | 0.015 | ||
Blastomere transfer | 1605 (61.5) | 5399 (64.1) | |
Blastocyst transfer | 1006 (38.6) | 3026 (35.9) | |
The day of development of frozen embryos | 0.115 | ||
Day 3 | 1605 (61.5) | 5396 (64.0) | |
Day 4 | 1 (0.0) | 3 (0.0) | |
Day 5 | 783 (30.0) | 2379 (28.2) | |
Day 6 | 222 (8.5) | 647 (7.7) | |
Good-quality rate of the embryo implanted | 1446 (56.8) | 4703 (55.4) | 0.188 |
Clinical outcomes | |||
Clinical pregnancy rate | 1326 (50.8) | 4708 (55.9) | < 0.001 |
Miscarriage rate | 253 (19.1) | 748 (15.9) | 0.006 |
Ectopic pregnancy rate | 44 (3.3) | 75 (1.6) | 0.006 |
Live birth rate | 1025 (39.3) | 3872 (46.0) | < 0.001 |
Multiple rated | 235 (22.9) | 1063 (27.5) | < 0.001 |
Continuous measurements are summarised as median (1st quartile–3rd quartile) if asymmetrically distributed. Nominal measurements are summarised as n (%) unless stated otherwise. AC-FET, artificial cycle; NC-LPS, natural cycles with luteal phase support; BMI, body mass index; FSH, follicle-stimulating hormone; ET, embryo transfer