Table 3.
Neonatal outcomes in singletons and multiples
| Singletons | Multiples | |||||
|---|---|---|---|---|---|---|
| AC-FET | NC-LPS | P value | AC-FET | NC-LPS | P value | |
| No. of neonatal | 787 | 2802 | 476 | 2140 | ||
| Stillbirth fetus | 5 (0.6) | 4 (0.1) | 0.029 | 8 (1.6) | 0 | |
| Pregnancies with a least one live born cycles | 782 | 2798 | 234a | 1070 | ||
| Gender: Male | 411 (52.2) | 1502 (53.6) | 0.493 | 272 (58.1) | 1142 (53.4) | 0.061 |
| Birth weight, g | 3400 (3100, 3700) | 3400 (3050, 3700) | 0.299 | 2550 (2150, 2900) | 2600 (2350, 2900) | 0.023 |
| Birth weight category (cases) | 0.502 | 0.245 | ||||
| ≤ 1500 g | 10 (2.3) | 45 (1.6) | 29 (6.1) | 104 (4.9) | ||
| 1500–2500 g | 35 (4.5) | 112 (4.0) | 192 (40.7) | 816 (38.2) | ||
| 2500 –4000 g | 679 (86.8) | 2445 (87.4) | 251 (53.2) | 1216 (56.9) | ||
| > 4000 g | 50 (6.4) | 196 (7.0) | – | – | ||
| Gestational age, weeks | 39.3 (38.4, 40.0) | 39.1 (38.4, 39.9) | 0.227 | 36.6 (35.3, 37.6) | 37.1 (36.1, 37.9) | < 0.001 |
| Gestational age category (cases) | 0.618 | < 0.001 | ||||
| < 32 weeks | 7 (0.9) | 14 (0.5) | 40 (8.5) | 76 (3.6) | ||
| 32–37 weeks | 54 (6.9) | 188 (6.7) | 231 (49.1) | 957 (44.9) | ||
| 37–42 weeks | 716 (92.0) | 2583 (92.6) | 199 (42.3) | 1097 (51.5) | ||
| > 42 weeks | 1 (0.1) | 5 (0.2) | – | – | ||
| z-score | 0.6 (0.0, 1.4) | 0.6 (− 0.1, 1.4) | 0.584 | − .5 (− 1.1, − 0.0) | − 0.4 (− 1.0, 0.2) | 0.009 |
| Small-for-gestational age | 30 (3.9) | 85 (3.1) | 0.266 | 79 (16.9) | 376 (18.0) | 0.220 |
| Large-for-gestational age | 222 (28.9) | 747 (27.1) | 0.378 | 13 (2.8) | 34 (1.6) | 0.085 |
| Early neonatal death | 3 (0.4) | 2 (0.1) | 0.073 | 5 (1.1) | 11 (0.5) | 0.188 |
| Late neonatal death | 1 (0.1) | 0 (0.0) | 0.218 | 4 (0.8) | 6 (0.3) | 0.089 |
| Infant death | 0 (0.0) | 1 (0.0) | 1.00 | 2 (0.4) | 1 (0.0) | 0.086 |
Values expressed as N (%) or median (1st quartile, 3rd quartile). P values are from Wilcoxon rank sum tests for continuous variables and the χ2 test or Fisher’s exact tests for categorical variables
a. 8 stillbirth fetus in 4 cycles