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. 2019 Apr 8;97(6):2342–2356. doi: 10.1093/jas/skz110

Table 3.

Apparent digestibility of nutrients of weaned pigs treated with KR-32 after challenged with or without enterotoxigenic Escherichia coli (ETEC) K88

Item Exp. 1 Exp. 2
Treatment group1 SEM P-value Treatment group2 SEM P-value
CON-1 APK CON-2 K88 K88+APK
OM, % 77.11 76.48 0.56 0.637 75.66 69.31 74.23 1.37 0.129
CP, % 70.33 71.33 0.68 0.539 69.66a 54.06b 63.50c 2.39 <0.01
Crude fat, % 69.23 70.54 1.27 0.662 71.03a 51.62b 67.01a 3.50 0.024
Ca, % 53.10 50.13 1.75 0.459 56.92 40.24 43.58 0.04 0.141
P, % 47.10 46.61 1.31 0.874 45.33 32.33 37.67 3.04 0.228

a–cMeans within a row with different superscripts differ (P < 0.05).

1CON-1 = piglets with an intraperitoneal (i.p.) injection of an equivalent volume (1 mL) of PBS; APK = piglets with an i.p. injection of antimicrobial peptide KR-32. n = 6 for the CON-1 group and n = 6 for the APK group.

2CON-2 = piglets with an oral administration of fresh Luria–Bertani broth (50 mL) followed by an i.p. injection of an equivalent volume of PBS; K88 = piglets orally challenged with 1 × 1010 cfu ETEC K88 on day 1 followed by an i.p. injection of an equivalent volume (1 mL) of PBS; K88 + APK = piglets orally challenged with 1 × 1010 cfu ETEC K88 on day 1 followed by an i.p. injection of 0.6 mg/kg KR-32. n = 6 for the CON-2 group, n = 5 for the K88 group, and n = 5 for the K88 + APK group.